
4-in-1 Urinary Tract Formula
Daily support for urinary tract and bladder health.* Powered by D-Mannose, cranberry, hibiscus, and dandelion, with every dose transparently listed on the label. Gentle enough for everyday use.
✔ No sugar-loaded juice required.
Built for everyday confidence, not occasional panic.
For the women who are tired of thinking about it.
The cranberry juice that’s mostly sugar. The water you chug “just in case.” The way part of your brain is always quietly running the math on it. If you’ve been there more than once, you know the worst part isn’t one bad day. It’s the constant low-grade vigilance.
That’s why D-Mannose has become one of the most talked-about ingredients for urinary tract support. Unlike cranberry, it works through a different mechanism, which is exactly why we pair both in our formula. Hibiscus and dandelion complete the blend for comprehensive daily support.*
Not something you reach for when things go wrong. Something you take so you can stop thinking about it.
Our 4-in-1 Urinary Tract Formula combines D-Mannose with cranberry, hibiscus, and dandelion for complementary daily support. Every dose is fully transparent. No sugar-loaded juice. Just one clean daily habit.*
Four jobs. One formula.
Each ingredient has a different role. Together, they create more comprehensive daily support than any single ingredient alone.*
Urinary Tract Support
D-Mannose · The foundationSupports urinary tract health through a unique mechanism that has made it one of the most recognized ingredients in the category.*
Bladder Comfort
Hibiscus · The sootherThe one you can feel: a botanical traditionally used to support everyday bladder comfort.*
Antioxidant Defense
Cranberry · The complementCranberry PACs complement D-Mannose by supporting urinary tract health through a different pathway.*
Daily Balance
Dandelion · The finisherSupports healthy fluid balance, so the whole formula works as one gentle daily routine.*
Four ingredients. Nothing hidden.
D-Mannose and cranberry don’t compete. They complement each other. Hibiscus and dandelion complete the formula, giving each ingredient a distinct role in one simple daily routine. Every dose is printed on the label, so you can check our work.
D-Mannose
Foundation · 1,000 mgSupports urinary tract health through its unique mechanism.*
Cranberry
Complement · 150 mgWorks differently than D-Mannose, helping create more comprehensive support.*
Hibiscus
Comfort · 100 mgTraditionally used to support bladder comfort.*
Dandelion
Balance · 100 mgSupports healthy fluid balance as part of a complete daily routine.*
One Complete Daily Formula
Each ingredient has a different job. Together, they create more complete daily support than any single ingredient alone.*
How it becomes part of your life.
This isn’t a rescue product. It’s a quiet daily habit, and here’s how it settles in.
Build the habit
- One simple daily routine
- No sugary cranberry juice
- Easy to stay consistent
Daily coverage
- The formula becomes part of your everyday wellness routine*
- Designed for consistency, not emergencies
- Gentle enough for daily use*
Stop thinking about it
- A routine that quietly supports your urinary tract every day*
- One less thing competing for your attention
- Peace of mind becomes the habit
Daily support is the strategy. That’s why every first order is backed by our 60-day guarantee.
Rated 4.8/5 by the women using it.
“I’ve used it for years and it’s the ONLY one that has controlled my UTIs.”
“Dr. recommended. Give it a try. I had chronic UTI’s, I feel like it has helped.”
“Great product. Really works. I usually get a UTI frequently, none for 3 months now.”
“Works very well for urinary tract health. I take it every day with lots of water. Highly recommend it.”
“Use it if you are prone to UTIs. It really works.”
“Give it a try. Has changed my bathroom routine.”
“I was skeptical at first but I’m happy to say my bladder felt more calm. I will absolutely be repurchasing.”
“It keeps me healthy throughout the month. Less UTI’s.”
“I have been using this for a while now, I do think it is helping. The price is right and shipping is on time.”
“I tried a lot but High Level was the one that made me happy after seeing my urine test with a good result.”
“I have not had a UTI in 2 months!”
“I tell my friends that it is wonderful and that it really works.”
Genuine reviews from verified purchasers, collected via Klaviyo Reviews. Testimonials reflect individual experiences and are not a guarantee of results.
High Level Science has been featured in
Side by side, it’s not close.
| 4-in-1 Formula | Cranberry Juice | D-Mannose Alone | |
|---|---|---|---|
| D-Mannose | ✓ | ✗ | ✓ |
| Cranberry PACs | ✓ | With sugar | ✗ |
| Bladder comfort + flow botanicals | ✓ | ✗ | ✗ |
| No added sugar | ✓ | ✗ | ✓ |
| Built for daily use | ✓ | ✗ | Varies |
| Third-party tested every lot | ✓ | ✗ | Varies |
| Sold at GNC nationwide | ✓ | ✗ | Varies |
Category comparison based on publicly available labels of leading urinary-health products, July 2026.
Built by people with reputations to lose.

Dr. David G. Rizik, MD
World-renowned, double board certified interventional cardiologist with 100+ published works. Every High Level Science formula is built to his standard: clinically studied dosages, clean ingredients, third-party testing on every lot.

Ashley Parker Angel
Multi-platinum recording artist, Broadway & television star, and High Level Science co-founder. The rule he set for every formula: every dose on the label, every lot tested.
Everything you’re wondering.
How do I take it?
Take two veggie capsules daily as directed on the label, with or without food. One bottle is a full 30-day supply, and it’s designed for everyday use.
Is this a treatment for UTIs?
No. This is a dietary supplement for daily urinary tract and bladder support, not a treatment, and not a substitute for antibiotics or medical care. If you have symptoms of an infection, see your healthcare provider.
Can I take it every day?
Yes, that’s exactly how it’s designed to be used. D-Mannose is gentle, barely metabolized by the body, and there’s no added sugar, which is why daily support is its whole strategy.*
Why not just drink cranberry juice?
Most cranberry juice is loaded with added sugar and light on the PACs that research actually focuses on. This formula delivers cranberry’s researched compounds plus D-Mannose, without the sugary juice.
Can I take it with medications?
Check with your physician or pharmacist before starting, as you should with any supplement, especially if you take diuretics or have kidney concerns.
How does the 60-day guarantee actually work?
Try it the way it was designed to be used. Take it every day. If you’re not satisfied within 60 days of delivery, we’ll refund your first order. No hoops, no restocking fees. Just email us. One guarantee claim per product, per customer.
Can I pause or cancel my subscription?
Anytime. Pause, skip a delivery, or cancel from your account page in a couple of clicks. No phone calls required.
Off your mind. On your side.
Support that quietly fits into your day, so urinary health doesn’t have to. One transparent formula designed to become one less thing to think about.*
The best urinary support is the kind you stop thinking about.
Choose Your Plan Starting at $27.74 per bottleThe guarantee, in plain terms
Try it the way it was designed to be used. Take it every day. If you’re not satisfied within 60 days of delivery, we’ll refund your first order. No hoops. No restocking fees. Just email us.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. It is a dietary supplement for daily urinary tract and bladder support; it is not a treatment for urinary tract infections and not a substitute for antibiotics or medical care. If you have symptoms of an infection, contact your healthcare provider. Testimonials reflect individual experiences and are not a guarantee of results. Guarantee covers your first order of each product, one claim per product, per customer. Always consult your physician before starting any supplement.

